Journal Title：Computational Biology And Chemistry

Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.

Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.

Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.

《計(jì)算生物學(xué)和化學(xué)》發(fā)表計(jì)算生命科學(xué)所有領(lǐng)域的原創(chuàng)研究論文和評(píng)論文章。特別歡迎在核酸和蛋白質(zhì)序列研究、分子進(jìn)化、分子遺傳學(xué)（功能基因組學(xué)和蛋白質(zhì)組學(xué)）、生物特定或化學(xué)生物學(xué)特定建模的理論和實(shí)踐以及核酸和蛋白質(zhì)的結(jié)構(gòu)生物學(xué)等領(lǐng)域做出具有主要計(jì)算成分的高質(zhì)量研究貢獻(xiàn)。生物信息學(xué)、系統(tǒng)生物學(xué)、生態(tài)學(xué)、計(jì)算藥理學(xué)、代謝、生物醫(yī)學(xué)工程、流行病學(xué)和統(tǒng)計(jì)遺傳學(xué)領(lǐng)域的極高質(zhì)量研究工作也將受到考慮。

鑒于其固有的不確定性，應(yīng)徹底驗(yàn)證蛋白質(zhì)建模和分子對(duì)接研究。在沒(méi)有實(shí)驗(yàn)結(jié)果進(jìn)行驗(yàn)證的情況下，應(yīng)使用分子動(dòng)力學(xué)模擬以及詳細(xì)的自由能計(jì)算等作為補(bǔ)充技術(shù)來(lái)支持主要結(jié)論。提交沒(méi)有額外生物學(xué)見(jiàn)解的過(guò)早建模練習(xí)將不予考慮。

評(píng)論文章通常由編輯委托撰寫，未經(jīng)明確邀請(qǐng)不得提交給期刊。但是，歡迎潛在作者發(fā)送簡(jiǎn)短（一到三頁(yè)）的概要，編輯將對(duì)其進(jìn)行評(píng)估。

Computational Biology And Chemistry創(chuàng)刊于2003年，由Elsevier Ltd出版商出版，收稿方向涵蓋生物 - 計(jì)算機(jī)：跨學(xué)科應(yīng)用全領(lǐng)域，此期刊水平偏中等偏靠后，在所屬細(xì)分領(lǐng)域中專業(yè)影響力一般，過(guò)審相對(duì)較易，如果您文章質(zhì)量佳，選擇此期刊，發(fā)表機(jī)率較高。平均審稿速度 約15.0個(gè)月 ，影響因子指數(shù)2.6，該期刊近期沒(méi)有被列入國(guó)際期刊預(yù)警名單，廣大學(xué)者值得一試。